Late-onset schizophrenia in child survivors of the holocaust.
نویسندگان
چکیده
According to the stress diathesis model, the probability of psychosis is increased in high-risk groups, a vulnerable one being the Holocaust child survivors. This study was conducted to inquire into the long-term effects of their Holocaust experience. We concentrated on a possible association between the onset of schizophrenia and the degree of persecution. Ninety-three medical files of Holocaust child survivors were recruited from sociomedical expert reports of the Restitution Office in Germany. The onset of schizophrenia was used as dependent variable in a categorical regression model. Regarding schizophrenia, exclusively late-onset schizophrenia could be diagnosed in our sample. Schizophrenia was significantly associated with the highest category of persecution (Fisher exact test, p < 0.001). In the categorical regression model, the category of persecution was a significant coefficient, only (F = 23.9, p < 0.001). The strong association between late onset of schizophrenia and the degree of persecution suggest an influence of stress exposure.
منابع مشابه
CHAPTER 2 Diurnal Cortisol Patterns and Stress Reactivity in Child Holocaust Survivors
Late-life implications of early traumatic stress for the adreno-cortical system were examined in a sample of 133 child survivors of the Holocaust,who were subjected to Nazi persecution during infancy. Method: In a non-convenience sample of child survivors, born between 1935-1944, basal circadian cortisol release and cortisol reactivity to a stressor were assessed. Results: Age, parental loss du...
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عنوان ژورنال:
- The Journal of nervous and mental disease
دوره 195 4 شماره
صفحات -
تاریخ انتشار 2007